Week 12 Team Project: Current Issues

Team assignments will be posted in Moodle.

Objectives

Read about and consider deeply one current issue relevant to the application of human genetic knowledge.
Create and review example infographics to communicate details about current issues in human genetics to a general audience.

Read & Discuss via Perusall each of your Team Resource reading(s) listed below - THIS TASK CAN BE COMPLETED FOR CREDIT UP TO THREE TIMES
Find & Share either a popular source or a scholarly source about your topic and provide a 1 paragraph (3-5 sentence) summary on your team’s discussion forum - THIS ACTIVITY CAN BE COMPLETED FOR CREDIT UP TO TWO TIMES.
Team Project Meeting, Thursday, 11:00 am - 12:20 pm (CT)
- Teams will work together to produce an infographic about their topic.

Pre-selected articles are listed below. Team discussion forums and shared google docs are available in Moodle.

Doudna 2020 The promise and challenge of therapeutic genome editing. https://doi.org/10.1038/s41586-020-1978-5
Gyngell Bowman-Smart Savulescu 2019 Moral reasons to edit the human genome- picking up from the Nuffield report. http://dx.doi.org/10.1136/medethics-2018-105084
Cohen 2019 The untold story of the ‘circle of trust’ behind the world’s first gene-edited babies. https://www.sciencemag.org/news/2019/08/untold-story-circle-trust-behind-world-s-first-gene-edited-babies

Treff et al 2019 Utility and First Clinical Application of Screening Embryos for Polygenic Disease Risk Reduction. https://doi.org/10.3389/fendo.2019.00845
Hashiloni-Dolev Nov-Klaiman Raz 2019 Pandora’s pregnancy: NIPT, CMA, and genome sequencing—A new era for prenatal genetic testing. https://doi.org/10.1002/pd.5495
Regaldo 2019 The world’s first Gattaca baby tests are finally here. https://www.technologyreview.com/2019/11/08/132018/polygenic-score-ivf-embryo-dna-tests-genomic-prediction-gattaca/

Katsanis 2020 Pedigrees and perpetrators: Uses of DNA and Genealogy in Forensic Investigations. https://doi.org/10.1146/annurev-genom-111819-084213
M’Charek & Wade 2020 Doing the individual and the collective in forensic genetics- governance, race and restitution. https://doi.org/10.1057/s41292-020-00193-6
Granja & Machado 2020 Forensic DNA phenotyping and its politics of legitimation and contestation- Views of forensic geneticists in Europe. https://doi.org/10.1177/0306312720945033

Khoury et al 2020 The intersection of genomics and big data with public health- Opportunities for precision public health. https://doi.org/10.1371/journal.pmed.1003373
Green et al 2020 Strategic vision for improving human health at The Forefront of Genomics. https://doi.org/10.1038/s41586-020-2817-4
van Westrhenen et al 2020 Pharmacogenomics of Antidepressant and Antipsychotic Treatment- How Far Have We Got and Where Are We Going? https://doi.org/10.3389/fpsyt.2020.00094

Resnick 2018 How scientists are learning to predict your future with your genes. https://www.vox.com/science-and-health/2018/8/23/17527708/genetics-genome-sequencing-gwas-polygenic-risk-score
Morris Davies Smith 2020 Can education be personalised using pupils’ genetic data. https://doi.org/10.7554/eLife.49962
Mostafavi et al 2020 Variable prediction accuracy of polygenic scores within an ancestry group. https://doi.org/10.7554/eLife.48376